Enzyme-triggered gelation: targeting proteases with internal cleavage sites.
نویسندگان
چکیده
A generalizable method for detecting protease activity via gelation is described. A recognition sequence is used to target the protease of interest while a second protease is used to remove the residual residues from the gelator scaffold. Using this approach, selective assays for both MMP-9 and PSA are demonstrated.
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عنوان ژورنال:
- Chemical communications
دوره 50 14 شماره
صفحات -
تاریخ انتشار 2014